Polynucleotides: Advanced Regenerative Skin Treatment
ENQUIRE NOWRather than adding volume or altering your facial structure, polynucleotides work to improve skin quality, elasticity and tissue repair at a cellular level, supporting your ongoing skin health.
At JB Aesthetics, polynucleotide treatments are always tailored to you. We take the time to understand what you would like to improve, and as a gentle, regenerative approach focused on supporting overall skin health, your skin will feel stronger, healthier and naturally refreshed.
At A Glance
TREATMENT TIME
30 minutes
NUMBING
Topical numbing cream if required
RECOVERY TIME
Immediate, with minimal downtime
RESULTS
Gradual improvement over several weeks, with optimal outcomes following a course of three treatments
What Are Polynucleotides?
Polynucleotides are naturally derived molecules that support your skin’s repair and renewal processes. When carefully injected into the skin by our doctors, they work by encouraging hydration and boosting collagen and elastin, helping your skin gradually feel stronger and healthier.
Over time, this can improve texture and overall skin quality in a subtle, natural way, which is why they are so well regarded at our clinic. They are particularly effective in delicate areas such as under the eyes and work well as part of your wider skincare and injectables journey.
Stimulates Skin Regeneration
Encourages cellular repair and tissue renewal.
Improves Skin Elasticity & Texture
Supports firmer, smoother and more resilient skin.
Enhances Hydration
Improves moisture retention for healthier-looking skin.
Natural, Progressive Results
Results develop gradually while maintaining a natural appearance.
Polynucleotides for Men & Women
Polynucleotides are suitable for both men and women. Treatment plans are adapted to skin type, lifestyle and individual goals.
For men, treatment often focuses on improving skin resilience and texture while maintaining a natural, understated appearance.
For women, treatment may prioritise elasticity, hydration and overall skin rejuvenation.
The JB Aesthetics Approach to Polynucleotides
Evidence-Based Practice
Treatments are guided by clinical evidence and best practice in aesthetic medicine.
Bespoke Treatment Planning
Every plan is tailored to facial anatomy, muscle strength and individual goals.
Conservative, Natural Results
The focus is on refreshing the face without stiffness or an artificial appearance.
Patient Safety First
JB Aesthetics is a doctor-led clinic with extensive experience in facial anatomy and injectable treatments. Safety and suitability are prioritised throughout.
Aftercare Guidance
What to Avoid
Alcohol and strenuous exercise for 24 hours
Excessive heat such as saunas and steam rooms for 24 hours
Applying pressure to or massaging treated areas unless advised by your clinician
RECOVERY Guidance
Mild redness or swelling at injection sites may occur
Skin improvements develop gradually over time
Full aftercare instructions will be provided following treatment
Frequently Asked Questions
What areas are commonly treated with Polynucleotides?
Face
Under-eye area
Neck
Décolletage
Hands
Who are Polynucleotides suitable for?
Notice thinning or crepey skin
Experience dullness or dehydration
Want to improve skin quality without filler
Are seeking a regenerative approach to ageing
Prefer subtle, long-term improvement
A consultation is required to assess suitability and develop a bespoke treatment plan.
How many polynucleotide treatments are needed?
When will results be visible?
Do polynucleotides add volume?
Are polynucleotides safe?
Can polynucleotides be used under the eyes?
Can polynucleotides be combined with other treatments?
Patient Reviews
JB Aesthetics is proud to hold a five-star rating on Google, with patients consistently praising the clinic’s professionalism, honesty and considered approach to facial aesthetics.
Book a Polynucleotides
Consultation in Marylebone
Polynucleotides at JB Aesthetics are ideal for patients seeking regenerative skin improvement delivered through a considered, doctor-led approach.