Polynucleotides are advanced regenerative injectables designed to improve skin quality, elasticity and tissue repair at a cellular level. Rather than adding volume or altering facial structure, polynucleotides support natural skin regeneration, improve hydration and contribute to long-term skin health.
At JB Aesthetics, polynucleotide treatments are delivered by qualified doctors as part of a personalised, evidence-based approach to regenerative aesthetics. Treatments are tailored to individual skin concerns, with a focus on gradual improvement and skin longevity.
At A Glance
TREATMENT TIME
30 minutes
NUMBING
Topical numbing cream if required
RECOVERY TIME
Immediate, with minimal downtime
RESULTS
Gradual improvement over several weeks, with optimal outcomes following a course of three treatments
What Are Polynucleotides?
Polynucleotides are naturally derived molecules that play an important role in cellular repair and regeneration. When injected into the skin, they stimulate fibroblast activity, enhance hydration and support collagen and elastin production.
This regenerative process helps improve skin texture, elasticity and resilience over time. Polynucleotides are particularly suited to delicate areas where traditional dermal fillers may not be appropriate, such as the under-eye region. Unlike hyaluronic acid dermal fillers, polynucleotides do not add volume or alter facial contours. The focus is on restoring skin health and improving quality from within.
Stimulates Skin Regeneration
Encourages cellular repair and tissue renewal.
Improves Skin Elasticity & Texture
Supports firmer, smoother and more resilient skin.
Enhances Hydration
Improves moisture retention for healthier-looking skin.
Natural, Progressive Results
Results develop gradually while maintaining a natural appearance.
Polynucleotides for Men & Women
Polynucleotides are suitable for both men and women. Treatment plans are adapted to skin type, lifestyle and individual goals.
For men, treatment often focuses on improving skin resilience and texture while maintaining a natural, understated appearance.
For women, treatment may prioritise elasticity, hydration and overall skin rejuvenation.
The JB Aesthetics Approach to Polynucleotides
Evidence-Based Practice
Treatments are guided by clinical evidence and best practice in aesthetic medicine.
Bespoke Treatment Planning
Every plan is tailored to facial anatomy, muscle strength and individual goals.
Conservative, Natural Results
The focus is on refreshing the face without stiffness or an artificial appearance.
Patient Safety First
JB Aesthetics is a doctor-led clinic with extensive experience in facial anatomy and injectable treatments. Safety and suitability are prioritised throughout.
Aftercare Guidance
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Alcohol and strenuous exercise for 24 hours
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Excessive heat such as saunas and steam rooms for 24 hours
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Applying pressure to or massaging treated areas unless advised by your clinician
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Mild redness or swelling at injection sites may occur
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Skin improvements develop gradually over time
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Full aftercare instructions will be provided following treatment
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Frequently Asked Questions
Polynucleotides can be used to treat a range of areas, including:
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Face
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Under-eye area
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Neck
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Décolletage
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Hands
Treatment areas are selected following a comprehensive skin assessment.
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Polynucleotides may be suitable for patients who:
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Notice thinning or crepey skin
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Experience dullness or dehydration
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Want to improve skin quality without filler
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Are seeking a regenerative approach to ageing
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Prefer subtle, long-term improvement
A consultation is required to assess suitability and develop a bespoke treatment plan.
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A course of three treatments is usually recommended for optimal results. This will be discussed during consultation.
Skin quality improvements develop gradually over several weeks as regeneration occurs.
No. Polynucleotides improve skin quality without adding volume or altering facial shape.
When administered by qualified doctors, polynucleotides are considered safe and well tolerated.
Yes. Polynucleotides are commonly used in the under-eye area where the skin is delicate.
Yes. They are often combined with Profhilo, Sunekos or other regenerative skin treatments.
Patient Reviews
JB Aesthetics is proud to hold a five-star rating on Google, with patients consistently praising the clinic’s professionalism, honesty and considered approach to facial aesthetics.
