POLYNUCLEOTIDES

Polynucleotides are biocompatible molecules derived from purified DNA, typically sourced from fish species such as salmon or trout. These agents are used in regenerative medicine due to their ability to stimulate cellular repair, modulate inflammation, and promote the production of collagen and extracellular matrix proteins.

When injected into the dermis, polynucleotides can help support the restoration of skin integrity, particularly in individuals experiencing tissue degradation, chronic inflammation, or environmental skin damage. Their mechanism of action includes hydration enhancement, fibroblast stimulation, and improved skin elasticity and barrier function.

Treatment may be considered in clinically appropriate cases to address early dermal atrophy, post-inflammatory changes, or general loss of structural skin resilience. All patients are assessed through a medical consultation to determine the therapeutic suitability of polynucleotide based intervention.

POLYNUCLEOTIDES - HOW DO THEY WORK?

Polynucleotides act at a cellular and molecular level, enhancing the skin’s natural regenerative functions. When administered intradermally, they support the following biological processes:

Tissue regeneration: By activating fibroblasts and other repair pathways, polynucleotides assist in the remodelling of damaged or ageing dermal structures, including areas affected by volume loss or reduced elasticity.
Hydration regulation: Due to their high water-binding capacity, polynucleotides support improved cutaneous hydration, which is essential in managing dry, compromised, or barrier-impaired skin.
Antioxidant activity: These molecules exhibit free radical scavenging properties, contributing to the protection of skin cells from oxidative and environmental stress.
Collagen synthesis stimulation: Over time, repeated treatment can enhance dermal firmness and density by encouraging the production of structural proteins such as collagen.

Polynucleotide-based therapy may be considered in clinically appropriate cases to manage:

Early signs of dermal atrophy and volume depletion
Structural laxity due to ageing or environmental damage
Post-inflammatory changes, including textural irregularities such as those following acne
Periorbital concerns, such as tissue thinning or discolouration under the eyes

Treatment areas include the under eye region, face, and neck, based on individual skin assessments performed by qualified healthcare professionals. Each patient receives a full clinical consultation to determine whether polynucleotide treatment is medically indicated as part of a broader dermal health or regenerative care plan.

What Results Can I Expect from a Polynucleotides Facial Treatment?

Polynucleotides offer a clinically supported approach to enhancing skin health, particularly in patients presenting with early signs of dermal degradation such as fine lines, irregular pigmentation, and tissue laxity. By stimulating fibroblast activity and promoting the production of collagen and elastin, this treatment supports cellular repair and contributes to improved dermal structure, hydration, and function.

Please note: All treatments require a full medical and psychosocial assessment to determine clinical appropriateness. Treatments are only provided where there is a clear therapeutic benefit, and we reserve the right to decline treatment if it is not deemed clinically suitable.

Frequently Asked Questions

HOW MANY SESSIONS DO I NEED?

For best results 3 sessions 2-3 weeks apart are advised, then maintenance every 3-6 months.

HOW LONG DOES THE TREATMENT TAKE?

15-30 minutes.

WHEN WILL I SEE RESULTS?

Many patients notice improved hydration and texture within days of their first session. The real magic, however, happens over the following weeks as collagen production ramps up.

ARE POLYNUCLEOTIDES SAFE?

Yes! Polynucleotides are derived from natural DNA sources and are fully biocompatible, meaning they integrate seamlessly with your skin. Side effects are minimal and may include slight redness or swelling at the injection sites, which typically resolves within 24–48 hours.

Book TREATMENT today

Polynucleotides rejuvenate the skin by stimulating repair, enhancing hydration, boosting collagen production and improving elasticity for a radiant, youthful appearance.

Polynucleotides £350-400

Email:

info@jbaesthetics.com

OUR CLINIC:

UNTIL, 1 Orchard Street, W1H 6HJ

Phone:

07774 569396